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SMILES: COCCOc1cccc2ccc(nc12)-c1cn(nn1)-c1ccc(F)cc1

InChI Key: InChIKey=YXRXABGBLQIFMN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM403758 (US10336721, Example 15 | US10968198, Example 15) Show SMILES COCCOc1cccc2ccc(nc12)-c1cn(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H17FN4O2/c1-26-11-12-27-19-4-2-3-14-5-10-17(22-20(14)19)18-13-25(24-23-18)16-8-6-15(21)7-9-16/h2-10,13H,11-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University US Patent					Assay Description Data obtained for the Example compounds, obtained using the methods described in Example B.				US Patent US10968198 (2021)
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM403758 (US10336721, Example 15 | US10968198, Example 15) Show SMILES COCCOc1cccc2ccc(nc12)-c1cn(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H17FN4O2/c1-26-11-12-27-19-4-2-3-14-5-10-17(22-20(14)19)18-13-25(24-23-18)16-8-6-15(21)7-9-16/h2-10,13H,11-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2RR1WNP
					More data for this Ligand-Target Pair