null

SMILES: FC(CCn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1)Cn1cc(nn1)C(=O)NCc1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=UEFQSWFMSOSYJP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405064 (1-[2-fluoro-4-(4-{2-[3- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1)Cn1cc(nn1)C(=O)NCc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C26H23F7N8O4/c27-18(13-41-14-21(36-38-41)24(43)34-12-17-4-2-6-20(10-17)45-26(31,32)33)7-8-40-15-22(37-39-40)35-23(42)11-16-3-1-5-19(9-16)44-25(28,29)30/h1-6,9-10,14-15,18H,7-8,11-13H2,(H,34,43)(H,35,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				Citation and Details BindingDB Entry DOI: 10.7270/Q20Z76GP
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405064 (1-[2-fluoro-4-(4-{2-[3- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1)Cn1cc(nn1)C(=O)NCc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C26H23F7N8O4/c27-18(13-41-14-21(36-38-41)24(43)34-12-17-4-2-6-20(10-17)45-26(31,32)33)7-8-40-15-22(37-39-40)35-23(42)11-16-3-1-5-19(9-16)44-25(28,29)30/h1-6,9-10,14-15,18H,7-8,11-13H2,(H,34,43)(H,35,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair