null

SMILES: FC(CCn1cc(nn1)C(=O)NCc1ccc(nc1)C(F)(F)F)Cn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1

InChI Key: InChIKey=UPHSQIVKYHXYHS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405067 (1-[3-fluoro-4-(4-{2-[3- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1ccc(nc1)C(F)(F)F)Cn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1 Show InChI InChI=1S/C25H22F7N9O3/c26-17(6-7-40-13-19(36-38-40)23(43)34-11-16-4-5-20(33-10-16)24(27,28)29)12-41-14-21(37-39-41)35-22(42)9-15-2-1-3-18(8-15)44-25(30,31)32/h1-5,8,10,13-14,17H,6-7,9,11-12H2,(H,34,43)(H,35,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				Citation and Details BindingDB Entry DOI: 10.7270/Q20Z76GP
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405067 (1-[3-fluoro-4-(4-{2-[3- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1ccc(nc1)C(F)(F)F)Cn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1 Show InChI InChI=1S/C25H22F7N9O3/c26-17(6-7-40-13-19(36-38-40)23(43)34-11-16-4-5-20(33-10-16)24(27,28)29)12-41-14-21(37-39-41)35-22(42)9-15-2-1-3-18(8-15)44-25(30,31)32/h1-5,8,10,13-14,17H,6-7,9,11-12H2,(H,34,43)(H,35,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair