BDBM409855 US10370333, Example IV-26

SMILES: COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O

InChI Key: InChIKey=SBAITEDLNTYIOE-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 409855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM409855 (US10370333, Example IV-26) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O Show InChI InChI=1S/C13H12ClN3O4S/c1-21-11-3-2-9(14)5-12(11)22(19,20)17-10-4-8(13(15)18)6-16-7-10/h2-7,17H,1H3,(H2,15,18)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD-BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...				US Patent US10370333 (2019) BindingDB Entry DOI: 10.7270/Q2445PVM
					More data for this Ligand-Target Pair
Intestinal alkaline phosphatase (Homo sapiens (Human))	BDBM409855 (US10370333, Example IV-26) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O Show InChI InChI=1S/C13H12ClN3O4S/c1-21-11-3-2-9(14)5-12(11)22(19,20)17-10-4-8(13(15)18)6-16-7-10/h2-7,17H,1H3,(H2,15,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford Burnham Prebys Medical Discovery Institute Curated by ChEMBL					Assay Description Inhibition of IAP (unknown origin)				Bioorg Med Chem Lett 28: 31-34 (2018) Article DOI: 10.1016/j.bmcl.2017.11.024 BindingDB Entry DOI: 10.7270/Q2PZ5CD9
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM409855 (US10370333, Example IV-26) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O Show InChI InChI=1S/C13H12ClN3O4S/c1-21-11-3-2-9(14)5-12(11)22(19,20)17-10-4-8(13(15)18)6-16-7-10/h2-7,17H,1H3,(H2,15,18)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Sanford Burnham Prebys Medical Discovery Institute Curated by ChEMBL					Assay Description Inhibition of TNAP (unknown origin) using PPi as substrate				Bioorg Med Chem Lett 28: 31-34 (2018) Article DOI: 10.1016/j.bmcl.2017.11.024 BindingDB Entry DOI: 10.7270/Q2PZ5CD9
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM409855 (US10370333, Example IV-26) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O Show InChI InChI=1S/C13H12ClN3O4S/c1-21-11-3-2-9(14)5-12(11)22(19,20)17-10-4-8(13(15)18)6-16-7-10/h2-7,17H,1H3,(H2,15,18)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Sanford Burnham Prebys Medical Discovery Institute Curated by ChEMBL					Assay Description Inhibition of TNAP (unknown origin) in whole blood using pNPP as substrate				Bioorg Med Chem Lett 28: 31-34 (2018) Article DOI: 10.1016/j.bmcl.2017.11.024 BindingDB Entry DOI: 10.7270/Q2PZ5CD9
					More data for this Ligand-Target Pair
Alkaline phosphatase placental type (Homo sapiens (Human))	BDBM409855 (US10370333, Example IV-26) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O Show InChI InChI=1S/C13H12ClN3O4S/c1-21-11-3-2-9(14)5-12(11)22(19,20)17-10-4-8(13(15)18)6-16-7-10/h2-7,17H,1H3,(H2,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford Burnham Prebys Medical Discovery Institute Curated by ChEMBL					Assay Description Inhibition of PLAP (unknown origin)				Bioorg Med Chem Lett 28: 31-34 (2018) Article DOI: 10.1016/j.bmcl.2017.11.024 BindingDB Entry DOI: 10.7270/Q2PZ5CD9
					More data for this Ligand-Target Pair