BDBM410096 US10370370, Compound 1-P2

SMILES: C1CN2CCC1[C@@H](C2)Nc1noc2ccccc12

InChI Key: InChIKey=XSLYDNDTJBUTKV-GFCCVEGCSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 410096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM410096 (US10370370, Compound 1-P2) Show SMILES C1CN2CCC1[C@@H](C2)Nc1noc2ccccc12 |r,wD:6.9,(-.03,-5,;-.03,-6.54,;1.31,-7.31,;.59,-5.96,;2.08,-5.56,;1.31,-4.23,;2.64,-5,;2.64,-6.54,;3.97,-4.23,;5.31,-5,;5.31,-6.54,;6.77,-7.01,;7.68,-5.77,;9.21,-5.6,;9.84,-4.2,;8.93,-2.95,;7.4,-3.11,;6.77,-4.52,)| Show InChI InChI=1S/C14H17N3O/c1-2-4-13-11(3-1)14(16-18-13)15-12-9-17-7-5-10(12)6-8-17/h1-4,10,12H,5-9H2,(H,15,16)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axovant Sciences GmbH US Patent					Assay Description α7 nAChR: The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affin...				US Patent US10370370 (2019) BindingDB Entry DOI: 10.7270/Q2348NRP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM410096 (US10370370, Compound 1-P2) Show SMILES C1CN2CCC1[C@@H](C2)Nc1noc2ccccc12 |r,wD:6.9,(-.03,-5,;-.03,-6.54,;1.31,-7.31,;.59,-5.96,;2.08,-5.56,;1.31,-4.23,;2.64,-5,;2.64,-6.54,;3.97,-4.23,;5.31,-5,;5.31,-6.54,;6.77,-7.01,;7.68,-5.77,;9.21,-5.6,;9.84,-4.2,;8.93,-2.95,;7.4,-3.11,;6.77,-4.52,)| Show InChI InChI=1S/C14H17N3O/c1-2-4-13-11(3-1)14(16-18-13)15-12-9-17-7-5-10(12)6-8-17/h1-4,10,12H,5-9H2,(H,15,16)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axovant Sciences GmbH US Patent					Assay Description h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...				US Patent US10370370 (2019) BindingDB Entry DOI: 10.7270/Q2348NRP
					More data for this Ligand-Target Pair