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SMILES: Fc1ccc2NCCCN3CCC(C3)Nc3ccn4ncc(-c1c2)c4n3

InChI Key: InChIKey=WRBBRPHOGZDXIG-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410705   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM410705
PNG
(US10377772, Compound N6)
Show SMILES Fc1ccc2NCCCN3CCC(C3)Nc3ccn4ncc(-c1c2)c4n3
Show InChI InChI=1S/C19H21FN6/c20-17-3-2-13-10-15(17)16-11-22-26-9-5-18(24-19(16)26)23-14-4-8-25(12-14)7-1-6-21-13/h2-3,5,9-11,14,21H,1,4,6-8,12H2,(H,23,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Oncodesign S.A.

US Patent


Assay Description
The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...

US Patent US10377772 (2019)


BindingDB Entry DOI: 10.7270/Q2251MJZ
More data for this
Ligand-Target Pair