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SMILES: Cc1cc(F)c-2cc1NC[C@@H]1CCCN1CCNc1ccn3ncc-2c3n1

InChI Key: InChIKey=RJHJHVLIHIPFKF-AWEZNQCLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410709   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM410709
PNG
(US10377772, Compound N10)
Show SMILES Cc1cc(F)c-2cc1NC[C@@H]1CCCN1CCNc1ccn3ncc-2c3n1 |r|
Show InChI InChI=1S/C20H23FN6/c1-13-9-17(21)15-10-18(13)23-11-14-3-2-6-26(14)8-5-22-19-4-7-27-20(25-19)16(15)12-24-27/h4,7,9-10,12,14,23H,2-3,5-6,8,11H2,1H3,(H,22,25)/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Oncodesign S.A.

US Patent


Assay Description
The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...

US Patent US10377772 (2019)


BindingDB Entry DOI: 10.7270/Q2251MJZ
More data for this
Ligand-Target Pair