null

SMILES: Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCNC(=O)[C@H](CO)NCc3cc2Cl)cccc1-c1ccccc1

InChI Key: InChIKey=DIVOZEFXJDQJLX-LJAQVGFWSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412142   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 [18-239,H172E]/protein 1 [25-167,N33K],P01857[99-330,C104S,C109S,C112S,L118I,P121S] (Homo sapiens (Human))	BDBM412142 (US10392405, Compound Id 1.006 | US11059834, Compou...) Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCNC(=O)[C@H](CO)NCc3cc2Cl)cccc1-c1ccccc1 |r| Show InChI InChI=1S/C33H33ClN4O5/c1-21-24(8-5-9-27(21)23-6-3-2-4-7-23)20-43-31-14-30-25(13-28(31)34)17-38-29(18-39)33(41)37-11-10-36-32(40)26-12-22(19-42-30)15-35-16-26/h2-9,12-16,29,38-39H,10-11,17-20H2,1H3,(H,36,40)(H,37,41)/t29-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM412142 (US10392405, Compound Id 1.006 | US11059834, Compou...) Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCNC(=O)[C@H](CO)NCc3cc2Cl)cccc1-c1ccccc1 |r| Show InChI InChI=1S/C33H33ClN4O5/c1-21-24(8-5-9-27(21)23-6-3-2-4-7-23)20-43-31-14-30-25(13-28(31)34)17-38-29(18-39)33(41)37-11-10-36-32(40)26-12-22(19-42-30)15-35-16-26/h2-9,12-16,29,38-39H,10-11,17-20H2,1H3,(H,36,40)(H,37,41)/t29-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...				US Patent US10392405 (2019) BindingDB Entry DOI: 10.7270/Q2057J9N
					More data for this Ligand-Target Pair