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SMILES: c1cc2c(nc(nc2[nH]1)-c1ccccn1)-n1ccc2cnccc12

InChI Key: InChIKey=XTCPFWHYKZIXMD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-2 (Homo sapiens (Human))	BDBM412744 (2-(pyridin-2-yl)-4-(1H-pyrrolo[3,2-c]pyridin-1-yl)...) Show SMILES c1cc2c(nc(nc2[nH]1)-c1ccccn1)-n1ccc2cnccc12 Show InChI InChI=1S/C18H12N6/c1-2-7-20-14(3-1)17-22-16-13(4-9-21-16)18(23-17)24-10-6-12-11-19-8-5-15(12)24/h1-11H,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myer Squibb Company US Patent					Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...				US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human))	BDBM412744 (2-(pyridin-2-yl)-4-(1H-pyrrolo[3,2-c]pyridin-1-yl)...) Show SMILES c1cc2c(nc(nc2[nH]1)-c1ccccn1)-n1ccc2cnccc12 Show InChI InChI=1S/C18H12N6/c1-2-7-20-14(3-1)17-22-16-13(4-9-21-16)18(23-17)24-10-6-12-11-19-8-5-15(12)24/h1-11H,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myer Squibb Company US Patent					Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...				US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N
					More data for this Ligand-Target Pair