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SMILES: COc1ccc(C)c(n1)C(=O)N1CC2CN(Cc3c(nc4ccccn34)-c3ccc(Cl)cc3)CC2C1

InChI Key: InChIKey=LFPZVWHVFXUWFL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM413565 (US10414765, Example 49) Show SMILES COc1ccc(C)c(n1)C(=O)N1CC2CN(Cc3c(nc4ccccn34)-c3ccc(Cl)cc3)CC2C1 Show InChI InChI=1S/C28H28ClN5O2/c1-18-6-11-25(36-2)31-26(18)28(35)33-15-20-13-32(14-21(20)16-33)17-23-27(19-7-9-22(29)10-8-19)30-24-5-3-4-12-34(23)24/h3-12,20-21H,13-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...				US Patent US10414765 (2019) BindingDB Entry DOI: 10.7270/Q2QJ7KNV
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM413565 (US10414765, Example 49) Show SMILES COc1ccc(C)c(n1)C(=O)N1CC2CN(Cc3c(nc4ccccn34)-c3ccc(Cl)cc3)CC2C1 Show InChI InChI=1S/C28H28ClN5O2/c1-18-6-11-25(36-2)31-26(18)28(35)33-15-20-13-32(14-21(20)16-33)17-23-27(19-7-9-22(29)10-8-19)30-24-5-3-4-12-34(23)24/h3-12,20-21H,13-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...				US Patent US10414765 (2019) BindingDB Entry DOI: 10.7270/Q2QJ7KNV
					More data for this Ligand-Target Pair