BDBM417063 4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxybenzamide ::US10456394, Example 1

SMILES: ONC(=O)c1ccc(CN2CCCc3ccccc23)cc1

InChI Key: InChIKey=NQVDRCWYKLNRPA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM417063 (4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...) Show SMILES ONC(=O)c1ccc(CN2CCCc3ccccc23)cc1 Show InChI InChI=1S/C17H18N2O2/c20-17(18-21)15-9-7-13(8-10-15)12-19-11-3-5-14-4-1-2-6-16(14)19/h1-2,4,6-10,21H,3,5,11-12H2,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.6	n/a	n/a	n/a	n/a	n/a	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS US Patent					Assay Description The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...				US Patent US10456394 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GFW
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM417063 (4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...) Show SMILES ONC(=O)c1ccc(CN2CCCc3ccccc23)cc1 Show InChI InChI=1S/C17H18N2O2/c20-17(18-21)15-9-7-13(8-10-15)12-19-11-3-5-14-4-1-2-6-16(14)19/h1-2,4,6-10,21H,3,5,11-12H2,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS US Patent					Assay Description The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...				US Patent US10456394 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GFW
					More data for this Ligand-Target Pair