BDBM417100 US10456394, Example 10

SMILES: CC1(C)CCc2cc(F)ccc2N1Cc1ccc(cc1)C(=O)NO

InChI Key: InChIKey=ZBEQGZLGWWZPPB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417100   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM417100 (US10456394, Example 10) Show SMILES CC1(C)CCc2cc(F)ccc2N1Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C19H21FN2O2/c1-19(2)10-9-15-11-16(20)7-8-17(15)22(19)12-13-3-5-14(6-4-13)18(23)21-24/h3-8,11,24H,9-10,12H2,1-2H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS US Patent					Assay Description The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...				US Patent US10456394 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GFW
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM417100 (US10456394, Example 10) Show SMILES CC1(C)CCc2cc(F)ccc2N1Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C19H21FN2O2/c1-19(2)10-9-15-11-16(20)7-8-17(15)22(19)12-13-3-5-14(6-4-13)18(23)21-24/h3-8,11,24H,9-10,12H2,1-2H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS US Patent					Assay Description The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...				US Patent US10456394 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GFW
					More data for this Ligand-Target Pair