null

SMILES: CCNC(=O)c1ccc(N2CCN(Cc3ccc4c5NCCCc5c(=O)[nH]c4c3)CC2)c(C)c1

InChI Key: InChIKey=NZDMYHLPDHCLGC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 419726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM419726 (US10464919, Example 64) Show SMILES CCNC(=O)c1ccc(N2CCN(Cc3ccc4c5NCCCc5c(=O)[nH]c4c3)CC2)c(C)c1 Show InChI InChI=1S/C27H33N5O2/c1-3-28-26(33)20-7-9-24(18(2)15-20)32-13-11-31(12-14-32)17-19-6-8-21-23(16-19)30-27(34)22-5-4-10-29-25(21)22/h6-9,15-16,29H,3-5,10-14,17H2,1-2H3,(H,28,33)(H,30,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.55	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair
Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM419726 (US10464919, Example 64) Show SMILES CCNC(=O)c1ccc(N2CCN(Cc3ccc4c5NCCCc5c(=O)[nH]c4c3)CC2)c(C)c1 Show InChI InChI=1S/C27H33N5O2/c1-3-28-26(33)20-7-9-24(18(2)15-20)32-13-11-31(12-14-32)17-19-6-8-21-23(16-19)30-27(34)22-5-4-10-29-25(21)22/h6-9,15-16,29H,3-5,10-14,17H2,1-2H3,(H,28,33)(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.38	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TNK1 (Homo sapiens (Human))	BDBM419726 (US10464919, Example 64) Show SMILES CCNC(=O)c1ccc(N2CCN(Cc3ccc4c5NCCCc5c(=O)[nH]c4c3)CC2)c(C)c1 Show InChI InChI=1S/C27H33N5O2/c1-3-28-26(33)20-7-9-24(18(2)15-20)32-13-11-31(12-14-32)17-19-6-8-21-23(16-19)30-27(34)22-5-4-10-29-25(21)22/h6-9,15-16,29H,3-5,10-14,17H2,1-2H3,(H,28,33)(H,30,34)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.2	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair