null

SMILES: Fc1cc(cc(F)c1N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1)C(=O)NC1CC1

InChI Key: InChIKey=QSDUGBPLSHIMHQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 419747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM419747 (US10464919, Example 85) Show SMILES Fc1cc(cc(F)c1N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1)C(=O)NC1CC1 Show InChI InChI=1S/C27H29F2N5O2/c28-21-13-17(26(35)31-18-4-5-18)14-22(29)25(21)34-10-8-33(9-11-34)15-16-3-6-19-23(12-16)32-27(36)20-2-1-7-30-24(19)20/h3,6,12-14,18,30H,1-2,4-5,7-11,15H2,(H,31,35)(H,32,36)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.87	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair
Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM419747 (US10464919, Example 85) Show SMILES Fc1cc(cc(F)c1N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1)C(=O)NC1CC1 Show InChI InChI=1S/C27H29F2N5O2/c28-21-13-17(26(35)31-18-4-5-18)14-22(29)25(21)34-10-8-33(9-11-34)15-16-3-6-19-23(12-16)32-27(36)20-2-1-7-30-24(19)20/h3,6,12-14,18,30H,1-2,4-5,7-11,15H2,(H,31,35)(H,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.3	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TNK1 (Homo sapiens (Human))	BDBM419747 (US10464919, Example 85) Show SMILES Fc1cc(cc(F)c1N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1)C(=O)NC1CC1 Show InChI InChI=1S/C27H29F2N5O2/c28-21-13-17(26(35)31-18-4-5-18)14-22(29)25(21)34-10-8-33(9-11-34)15-16-3-6-19-23(12-16)32-27(36)20-2-1-7-30-24(19)20/h3,6,12-14,18,30H,1-2,4-5,7-11,15H2,(H,31,35)(H,32,36)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.8	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair