null

SMILES: Clc1cc(cnc1N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1)C#N

InChI Key: InChIKey=DBTLGWQFPVIXTJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TNK1 (Homo sapiens (Human))	BDBM419795 (US10464919, Example 133) Show SMILES Clc1cc(cnc1N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1)C#N Show InChI InChI=1S/C23H23ClN6O/c24-19-10-16(12-25)13-27-22(19)30-8-6-29(7-9-30)14-15-3-4-17-20(11-15)28-23(31)18-2-1-5-26-21(17)18/h3-4,10-11,13,26H,1-2,5-9,14H2,(H,28,31)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.2	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM419795 (US10464919, Example 133) Show SMILES Clc1cc(cnc1N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1)C#N Show InChI InChI=1S/C23H23ClN6O/c24-19-10-16(12-25)13-27-22(19)30-8-6-29(7-9-30)14-15-3-4-17-20(11-15)28-23(31)18-2-1-5-26-21(17)18/h3-4,10-11,13,26H,1-2,5-9,14H2,(H,28,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.29	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair