null
SMILES: O=c1[nH]c2cc(CN3CCN(CC3)c3nc(ns3)C#N)ccc2c2NCCCc12
InChI Key: InChIKey=CBRIZHZYFLCPAP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM419807 (US10464919, Example 145) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Je Il Pharmaceutical Co., Ltd. US Patent | Assay Description The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p... | US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activated CDC42 kinase 1 (Homo sapiens (Human)) | BDBM419807 (US10464919, Example 145) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.24 | n/a | n/a | n/a | n/a | n/a | n/a |
Je Il Pharmaceutical Co., Ltd. US Patent | Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ... | US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TNK1 (Homo sapiens (Human)) | BDBM419807 (US10464919, Example 145) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.29 | n/a | n/a | n/a | n/a | n/a | n/a |
Je Il Pharmaceutical Co., Ltd. US Patent | Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ... | US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M | |||||||||||
More data for this Ligand-Target Pair |