null
SMILES: CCC(C)Oc1cc(Br)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-binding protein RBBP4/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 (Homo sapiens (Human)) | BDBM420317![]() (5-Bromo-3-(sec-butoxy)-N-((4,6-dimethyl-2-oxo-1,2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet ![]() | UniChem | US Patent | n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE LLC US Patent | Assay Description Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com... | US Patent US10478426 (2019) BindingDB Entry DOI: 10.7270/Q2M61NMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-binding protein RBBP4/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 (Homo sapiens (Human)) | BDBM420317![]() (5-Bromo-3-(sec-butoxy)-N-((4,6-dimethyl-2-oxo-1,2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet ![]() | UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE LLC US Patent | Assay Description Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com... | US Patent US10478426 (2019) BindingDB Entry DOI: 10.7270/Q2M61NMK | |||||||||||
More data for this Ligand-Target Pair |