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SMILES: NC1Cc2c(OC1c1cc(F)c(F)cc1F)ccc1ccc(cc21)C#N

InChI Key: InChIKey=SVNYWTMKYBTEHJ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420412   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM420412
PNG
(US10479798, Compound 11)
Show SMILES NC1Cc2c(OC1c1cc(F)c(F)cc1F)ccc1ccc(cc21)C#N |w:1.0,6.7|
Show InChI InChI=1S/C20H13F3N2O/c21-15-8-17(23)16(22)6-14(15)20-18(25)7-13-12-5-10(9-24)1-2-11(12)3-4-19(13)26-20/h1-6,8,18,20H,7,25H2
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MMDB

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n/an/a 205n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...

US Patent US10479798 (2019)


BindingDB Entry DOI: 10.7270/Q2377C4Z
More data for this
Ligand-Target Pair