BDBM42119 2-[4-(2,5-dimethyl-1-pyrrolyl)phenoxy]acetic acid::2-[4-(2,5-dimethylpyrrol-1-yl)phenoxy]acetic acid::2-[4-(2,5-dimethylpyrrol-1-yl)phenoxy]ethanoic acid::BIM-0001419.P001::cid_776871
SMILES: Cc1ccc(C)n1-c1ccc(OCC(O)=O)cc1
InChI Key: InChIKey=VKHKAGOXFDDDIY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Apurinic-apyrimidinic endonuclease 1 (APE-1) (Homo sapiens (Human)) | BDBM42119 (2-[4-(2,5-dimethyl-1-pyrrolyl)phenoxy]acetic acid ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal hexa-His tagged human APE1 expressed in Escherichia coli BL21 (Rosetta) using fluorescein-dabcyl-containing oligonucleotide ... | Bioorg Med Chem 25: 2531-2544 (2017) Article DOI: 10.1016/j.bmc.2017.01.028 BindingDB Entry DOI: 10.7270/Q2P55R4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
nuclear receptor subfamily 4, group A, member 1 (Homo sapiens (Human)) | BDBM42119 (2-[4-(2,5-dimethyl-1-pyrrolyl)phenoxy]acetic acid ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents | PCBioAssay | n/a | n/a | n/a | n/a | 8.75E+3 | n/a | n/a | n/a | n/a |
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2R78CMH | |||||||||||
More data for this Ligand-Target Pair |