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SMILES: Cn1c2cc(ccc2n(Cc2ccncc2)c1=O)S(=O)(=O)NC1(C)CC1

InChI Key: InChIKey=BXSREGQTRAKVQW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421422 (US10508086, Example 13 | US10995073, Example 13) Show SMILES Cn1c2cc(ccc2n(Cc2ccncc2)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C18H20N4O3S/c1-18(7-8-18)20-26(24,25)14-3-4-15-16(11-14)21(2)17(23)22(15)12-13-5-9-19-10-6-13/h3-6,9-11,20H,7-8,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.12E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021)
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421422 (US10508086, Example 13 | US10995073, Example 13) Show SMILES Cn1c2cc(ccc2n(Cc2ccncc2)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C18H20N4O3S/c1-18(7-8-18)20-26(24,25)14-3-4-15-16(11-14)21(2)17(23)22(15)12-13-5-9-19-10-6-13/h3-6,9-11,20H,7-8,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.12E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair