null

SMILES: CC1(CC1)NS(=O)(=O)c1ccc2CCN(C(=O)CN3CCOC3=O)c2c1

InChI Key: InChIKey=QMHBFTDPSONVFY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 421423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421423 (N-(1-Methylcyclopropyl)-1-[2-(2-oxooxazolidin-3-yl...) Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2CCN(C(=O)CN3CCOC3=O)c2c1 Show InChI InChI=1S/C17H21N3O5S/c1-17(5-6-17)18-26(23,24)13-3-2-12-4-7-20(14(12)10-13)15(21)11-19-8-9-25-16(19)22/h2-3,10,18H,4-9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.28E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair
ADP-ribosylhydrolase ARH3 (Homo sapiens (Human))	BDBM421423 (N-(1-Methylcyclopropyl)-1-[2-(2-oxooxazolidin-3-yl...) Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2CCN(C(=O)CN3CCOC3=O)c2c1 Show InChI InChI=1S/C17H21N3O5S/c1-17(5-6-17)18-26(23,24)13-3-2-12-4-7-20(14(12)10-13)15(21)11-19-8-9-25-16(19)22/h2-3,10,18H,4-9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM421423 (N-(1-Methylcyclopropyl)-1-[2-(2-oxooxazolidin-3-yl...) Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2CCN(C(=O)CN3CCOC3=O)c2c1 Show InChI InChI=1S/C17H21N3O5S/c1-17(5-6-17)18-26(23,24)13-3-2-12-4-7-20(14(12)10-13)15(21)11-19-8-9-25-16(19)22/h2-3,10,18H,4-9,11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARP1 In vitro selectivity assays were conducted as a 10 ul reaction volume in a NUNC Maxisorp 384-well assay plate pre-coated in-house with Histones...				US Patent US10995073 (2021)
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421423 (N-(1-Methylcyclopropyl)-1-[2-(2-oxooxazolidin-3-yl...) Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2CCN(C(=O)CN3CCOC3=O)c2c1 Show InChI InChI=1S/C17H21N3O5S/c1-17(5-6-17)18-26(23,24)13-3-2-12-4-7-20(14(12)10-13)15(21)11-19-8-9-25-16(19)22/h2-3,10,18H,4-9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.28E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021)
					More data for this Ligand-Target Pair
ADP-ribosylhydrolase ARH3 (Homo sapiens (Human))	BDBM421423 (N-(1-Methylcyclopropyl)-1-[2-(2-oxooxazolidin-3-yl...) Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2CCN(C(=O)CN3CCOC3=O)c2c1 Show InChI InChI=1S/C17H21N3O5S/c1-17(5-6-17)18-26(23,24)13-3-2-12-4-7-20(14(12)10-13)15(21)11-19-8-9-25-16(19)22/h2-3,10,18H,4-9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...				US Patent US10995073 (2021)
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM421423 (N-(1-Methylcyclopropyl)-1-[2-(2-oxooxazolidin-3-yl...) Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2CCN(C(=O)CN3CCOC3=O)c2c1 Show InChI InChI=1S/C17H21N3O5S/c1-17(5-6-17)18-26(23,24)13-3-2-12-4-7-20(14(12)10-13)15(21)11-19-8-9-25-16(19)22/h2-3,10,18H,4-9,11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARP1 In vitro selectivity assays were conducted as a 10 ul reaction volume in a NUNC Maxisorp 384-well assay plate pre-coated in-house with Histones...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair