null

SMILES: Cc1ccc(Cn2c3ccc(cc3n(C)c2=O)S(=O)(=O)NC2(C)CC2)o1

InChI Key: InChIKey=NGBTVZXISQGIRM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421429 (US10508086, Example 20 | US10995073, Example 20) Show SMILES Cc1ccc(Cn2c3ccc(cc3n(C)c2=O)S(=O)(=O)NC2(C)CC2)o1 Show InChI InChI=1S/C18H21N3O4S/c1-12-4-5-13(25-12)11-21-15-7-6-14(10-16(15)20(3)17(21)22)26(23,24)19-18(2)8-9-18/h4-7,10,19H,8-9,11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421429 (US10508086, Example 20 | US10995073, Example 20) Show SMILES Cc1ccc(Cn2c3ccc(cc3n(C)c2=O)S(=O)(=O)NC2(C)CC2)o1 Show InChI InChI=1S/C18H21N3O4S/c1-12-4-5-13(25-12)11-21-15-7-6-14(10-16(15)20(3)17(21)22)26(23,24)19-18(2)8-9-18/h4-7,10,19H,8-9,11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair