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SMILES: Cn1c2ccc(cc2n(-c2ccsc2)c1=O)S(=O)(=O)NC1(C)CC1

InChI Key: InChIKey=PUGBQIDRNJLBPD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421435 (US10508086, Example 26 | US10995073, Example 26) Show SMILES Cn1c2ccc(cc2n(-c2ccsc2)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C16H17N3O3S2/c1-16(6-7-16)17-24(21,22)12-3-4-13-14(9-12)19(15(20)18(13)2)11-5-8-23-10-11/h3-5,8-10,17H,6-7H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.99E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421435 (US10508086, Example 26 | US10995073, Example 26) Show SMILES Cn1c2ccc(cc2n(-c2ccsc2)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C16H17N3O3S2/c1-16(6-7-16)17-24(21,22)12-3-4-13-14(9-12)19(15(20)18(13)2)11-5-8-23-10-11/h3-5,8-10,17H,6-7H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.99E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair