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SMILES: Cn1c2ccc(cc2n(C(=O)c2ccccc2)c1=O)S(=O)(=O)NC1(C)CC1

InChI Key: InChIKey=XZVANOBBVZYUOO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421436 (US10508086, Example 27 | US10995073, Example 27) Show SMILES Cn1c2ccc(cc2n(C(=O)c2ccccc2)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C19H19N3O4S/c1-19(10-11-19)20-27(25,26)14-8-9-15-16(12-14)22(18(24)21(15)2)17(23)13-6-4-3-5-7-13/h3-9,12,20H,10-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	925	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421436 (US10508086, Example 27 | US10995073, Example 27) Show SMILES Cn1c2ccc(cc2n(C(=O)c2ccccc2)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C19H19N3O4S/c1-19(10-11-19)20-27(25,26)14-8-9-15-16(12-14)22(18(24)21(15)2)17(23)13-6-4-3-5-7-13/h3-9,12,20H,10-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	925	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair