null

SMILES: Cc1ccc(cc1)C(=O)n1c2cc(ccc2n(C)c1=O)S(=O)(=O)NC1(C)CC1

InChI Key: InChIKey=NDVZOYVBQJDKBL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421438 (US10508086, Example 29 | US10995073, Example 29) Show SMILES Cc1ccc(cc1)C(=O)n1c2cc(ccc2n(C)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C20H21N3O4S/c1-13-4-6-14(7-5-13)18(24)23-17-12-15(8-9-16(17)22(3)19(23)25)28(26,27)21-20(2)10-11-20/h4-9,12,21H,10-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.46E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021)
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421438 (US10508086, Example 29 | US10995073, Example 29) Show SMILES Cc1ccc(cc1)C(=O)n1c2cc(ccc2n(C)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C20H21N3O4S/c1-13-4-6-14(7-5-13)18(24)23-17-12-15(8-9-16(17)22(3)19(23)25)28(26,27)21-20(2)10-11-20/h4-9,12,21H,10-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.46E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair