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SMILES: Cn1c2cc(ccc2n(Cc2ccc(cc2)C#N)c1=O)S(=O)(=O)NC1(C)CC1

InChI Key: InChIKey=FRECDOYNTNTCJC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421454 (US10508086, Example 45 | US10995073, Example 45) Show SMILES Cn1c2cc(ccc2n(Cc2ccc(cc2)C#N)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C20H20N4O3S/c1-20(9-10-20)22-28(26,27)16-7-8-17-18(11-16)23(2)19(25)24(17)13-15-5-3-14(12-21)4-6-15/h3-8,11,22H,9-10,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421454 (US10508086, Example 45 | US10995073, Example 45) Show SMILES Cn1c2cc(ccc2n(Cc2ccc(cc2)C#N)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C20H20N4O3S/c1-20(9-10-20)22-28(26,27)16-7-8-17-18(11-16)23(2)19(25)24(17)13-15-5-3-14(12-21)4-6-15/h3-8,11,22H,9-10,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair