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SMILES: Cn1c2cc(ccc2n(Cc2ccccc2C(F)(F)F)c1=O)S(=O)(=O)NC1(C)CC1

InChI Key: InChIKey=UOCZWRGZTPKHSQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421455 (US10508086, Example 46 | US10995073, Example 46) Show SMILES Cn1c2cc(ccc2n(Cc2ccccc2C(F)(F)F)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C20H20F3N3O3S/c1-19(9-10-19)24-30(28,29)14-7-8-16-17(11-14)25(2)18(27)26(16)12-13-5-3-4-6-15(13)20(21,22)23/h3-8,11,24H,9-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.75E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421455 (US10508086, Example 46 | US10995073, Example 46) Show SMILES Cn1c2cc(ccc2n(Cc2ccccc2C(F)(F)F)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C20H20F3N3O3S/c1-19(9-10-19)24-30(28,29)14-7-8-16-17(11-14)25(2)18(27)26(16)12-13-5-3-4-6-15(13)20(21,22)23/h3-8,11,24H,9-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.75E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair