null

SMILES: Cn1c2cc(ccc2n(Cc2cc(Cl)cc(Cl)c2)c1=O)S(=O)(=O)NC1(C)CC1

InChI Key: InChIKey=UCCCXAOGQXANMY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421457 (US10508086, Example 48 | US10995073, Example 48) Show SMILES Cn1c2cc(ccc2n(Cc2cc(Cl)cc(Cl)c2)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C19H19Cl2N3O3S/c1-19(5-6-19)22-28(26,27)15-3-4-16-17(10-15)23(2)18(25)24(16)11-12-7-13(20)9-14(21)8-12/h3-4,7-10,22H,5-6,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.83E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421457 (US10508086, Example 48 | US10995073, Example 48) Show SMILES Cn1c2cc(ccc2n(Cc2cc(Cl)cc(Cl)c2)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C19H19Cl2N3O3S/c1-19(5-6-19)22-28(26,27)15-3-4-16-17(10-15)23(2)18(25)24(16)11-12-7-13(20)9-14(21)8-12/h3-4,7-10,22H,5-6,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.83E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair