null

SMILES: COCCn1c2cc(F)c(cc2n(-c2nnc(s2)C(F)F)c1=O)S(=O)(=O)NC1(CF)CC1

InChI Key: InChIKey=OOVXXUQLIFXKOC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421577 (BDBM495207 | US10508086, Example 167) Show SMILES COCCn1c2cc(F)c(cc2n(-c2nnc(s2)C(F)F)c1=O)S(=O)(=O)NC1(CF)CC1 Show InChI InChI=1S/C17H17F4N5O4S2/c1-30-5-4-25-10-6-9(19)12(32(28,29)24-17(8-18)2-3-17)7-11(10)26(16(25)27)15-23-22-14(31-15)13(20)21/h6-7,13,24H,2-5,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	74	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421577 (BDBM495207 | US10508086, Example 167) Show SMILES COCCn1c2cc(F)c(cc2n(-c2nnc(s2)C(F)F)c1=O)S(=O)(=O)NC1(CF)CC1 Show InChI InChI=1S/C17H17F4N5O4S2/c1-30-5-4-25-10-6-9(19)12(32(28,29)24-17(8-18)2-3-17)7-11(10)26(16(25)27)15-23-22-14(31-15)13(20)21/h6-7,13,24H,2-5,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	74	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair