BDBM42197 10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine::10-(4-chlorophenyl)[1,3]thiazolo[3,2-a]perimidine::10-(4-chlorophenyl)thiazolo[3,2-a]perimidine::MLS000594502::SMR000115638::cid_1818715

SMILES: Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12

InChI Key: InChIKey=QRFUTURFHZKKPS-UHFFFAOYSA-N

Data: 10 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 42197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
YopH (Yersinia enterocolitica)	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2794330
					More data for this Ligand-Target Pair
YopH (Yersinia enterocolitica)	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2C24TVC
					More data for this Ligand-Target Pair
YopH (Yersinia enterocolitica)	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2GT5KKS
					More data for this Ligand-Target Pair
streptokinase A precursor (Streptococcus pyogenes M1 GAS)	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair
SUMO/sentrin specific peptidase family member 8 (Homo sapiens (Human))	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MS3R7H
					More data for this Ligand-Target Pair
tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2WS8RXV
					More data for this Ligand-Target Pair
Caspase-3 (Homo sapiens (Human))	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	7.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2RJ4GZT
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2JS9NZB
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2F18X8S
					More data for this Ligand-Target Pair
Caspase-9 (Homo sapiens (Human))	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	8.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q25M647F
					More data for this Ligand-Target Pair
SUMO-1-specific protease (Homo sapiens (Human))	BDBM42197 (10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine...) Show SMILES Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12 Show InChI InChI=1S/C19H11ClN2S/c20-14-9-7-12(8-10-14)17-11-23-19-21-15-5-1-3-13-4-2-6-16(18(13)15)22(17)19/h1-11H	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q27H1H10
					More data for this Ligand-Target Pair