null

SMILES: COc1cccc2[nH]c(cc12)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COCc1ccccc1

InChI Key: InChIKey=KPARVBIJDYMZRF-LNBJVWSJSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 423430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM423430 (WO2005113580-Ex-28) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COCc1ccccc1 Show InChI InChI=1S/C32H40N4O6/c1-20(2)15-27(36(3)32(40)26-17-23-24(34-26)11-8-12-29(23)41-4)31(39)35-25(16-22-13-14-33-30(22)38)28(37)19-42-18-21-9-6-5-7-10-21/h5-12,17,20,22,25,27,34H,13-16,18-19H2,1-4H3,(H,33,38)(H,35,39)/t22-,25-,27-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO	n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
Pfizer Inc.					Assay Description Protection from SARS Infection: Neutral Red Endpoint The ability of compounds to protect cells against infection by the SARS coronavirus is measured ...				WIPO (2005) BindingDB Entry DOI: 10.7270/Q2PV6NRF
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM423430 (WO2005113580-Ex-28) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COCc1ccccc1 Show InChI InChI=1S/C32H40N4O6/c1-20(2)15-27(36(3)32(40)26-17-23-24(34-26)11-8-12-29(23)41-4)31(39)35-25(16-22-13-14-33-30(22)38)28(37)19-42-18-21-9-6-5-7-10-21/h5-12,17,20,22,25,27,34H,13-16,18-19H2,1-4H3,(H,33,38)(H,35,39)/t22-,25-,27-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO	n/a	n/a	927	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.					Assay Description The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...				WIPO (2005) BindingDB Entry DOI: 10.7270/Q2PV6NRF
					More data for this Ligand-Target Pair