null

SMILES: CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COC(=O)c1c(Cl)cccc1Cl

InChI Key: InChIKey=SXXAXVNCBPVURL-WBAXXEDZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 423451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM423451 (WO2005113580-Ex-53) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COC(=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C23H29Cl2N3O6/c1-12(2)9-18(27-13(3)29)22(32)28-17(10-14-7-8-26-21(14)31)19(30)11-34-23(33)20-15(24)5-4-6-16(20)25/h4-6,12,14,17-18H,7-11H2,1-3H3,(H,26,31)(H,27,29)(H,28,32)/t14-,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO	n/a	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a
Pfizer Inc.					Assay Description Protection from SARS Infection: Neutral Red Endpoint The ability of compounds to protect cells against infection by the SARS coronavirus is measured ...				WIPO (2005) BindingDB Entry DOI: 10.7270/Q2PV6NRF
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM423451 (WO2005113580-Ex-53) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COC(=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C23H29Cl2N3O6/c1-12(2)9-18(27-13(3)29)22(32)28-17(10-14-7-8-26-21(14)31)19(30)11-34-23(33)20-15(24)5-4-6-16(20)25/h4-6,12,14,17-18H,7-11H2,1-3H3,(H,26,31)(H,27,29)(H,28,32)/t14-,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.					Assay Description The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...				WIPO (2005) BindingDB Entry DOI: 10.7270/Q2PV6NRF
					More data for this Ligand-Target Pair