null

SMILES: Cc1nnn(C)c1-c1cnc2c(cn(CC3CCC(F)(F)CC3)c2c1)-c1cnn(CC(F)(F)F)c1

InChI Key: InChIKey=YBLPAUZBPXRQOM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM425406 (1-[(4,4-difluorocyclohexyl)methyl]-6- (3,5-dimethy...) Show SMILES Cc1nnn(C)c1-c1cnc2c(cn(CC3CCC(F)(F)CC3)c2c1)-c1cnn(CC(F)(F)F)c1 Show InChI InChI=1S/C23H24F5N7/c1-14-21(33(2)32-31-14)16-7-19-20(29-8-16)18(17-9-30-35(11-17)13-23(26,27)28)12-34(19)10-15-3-5-22(24,25)6-4-15/h7-9,11-12,15H,3-6,10,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent									US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [44-164] (Homo sapiens (Human))	BDBM425406 (1-[(4,4-difluorocyclohexyl)methyl]-6- (3,5-dimethy...) Show SMILES Cc1nnn(C)c1-c1cnc2c(cn(CC3CCC(F)(F)CC3)c2c1)-c1cnn(CC(F)(F)F)c1 Show InChI InChI=1S/C23H24F5N7/c1-14-21(33(2)32-31-14)16-7-19-20(29-8-16)18(17-9-30-35(11-17)13-23(26,27)28)12-34(19)10-15-3-5-22(24,25)6-4-15/h7-9,11-12,15H,3-6,10,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...				US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair