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SMILES: C[C@@]1(Cl)[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O[C@H]1n1cnc2c(N)nc(Cl)nc12
InChI Key: InChIKey=MPNAVWOMKHXPBY-GITKWUPZSA-L
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C Virus (Virus)) | BDBM426316![]() (US10513534, Compound 404) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent | US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C Virus (Virus)) | BDBM426316![]() (US10513534, Compound 404) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent | Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac... | US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ | |||||||||||
More data for this Ligand-Target Pair |