Found 4 hits for monomerid = 426550 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM426550
(US10526329, Compound 188 | US11072611, Compound 18...)Show SMILES CCc1nc2ccc(cn2c1N(C)c1nc(ns1)-c1ccc(Cl)cc1)N1CCN(CC1)S(C)(=O)=O Show InChI InChI=1S/C23H26ClN7O2S2/c1-4-19-22(28(2)23-26-21(27-34-23)16-5-7-17(24)8-6-16)31-15-18(9-10-20(31)25-19)29-11-13-30(14-12-29)35(3,32)33/h5-10,15H,4,11-14H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV
US Patent
| Assay Description
Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil... |
US Patent US10526329 (2020)
BindingDB Entry DOI: 10.7270/Q2Z60RGR |
More data for this
Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM426550
(US10526329, Compound 188 | US11072611, Compound 18...)Show SMILES CCc1nc2ccc(cn2c1N(C)c1nc(ns1)-c1ccc(Cl)cc1)N1CCN(CC1)S(C)(=O)=O Show InChI InChI=1S/C23H26ClN7O2S2/c1-4-19-22(28(2)23-26-21(27-34-23)16-5-7-17(24)8-6-16)31-15-18(9-10-20(31)25-19)29-11-13-30(14-12-29)35(3,32)33/h5-10,15H,4,11-14H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q241716Z |
More data for this
Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM426550
(US10526329, Compound 188 | US11072611, Compound 18...)Show SMILES CCc1nc2ccc(cn2c1N(C)c1nc(ns1)-c1ccc(Cl)cc1)N1CCN(CC1)S(C)(=O)=O Show InChI InChI=1S/C23H26ClN7O2S2/c1-4-19-22(28(2)23-26-21(27-34-23)16-5-7-17(24)8-6-16)31-15-18(9-10-20(31)25-19)29-11-13-30(14-12-29)35(3,32)33/h5-10,15H,4,11-14H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q241716Z |
More data for this
Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM426550
(US10526329, Compound 188 | US11072611, Compound 18...)Show SMILES CCc1nc2ccc(cn2c1N(C)c1nc(ns1)-c1ccc(Cl)cc1)N1CCN(CC1)S(C)(=O)=O Show InChI InChI=1S/C23H26ClN7O2S2/c1-4-19-22(28(2)23-26-21(27-34-23)16-5-7-17(24)8-6-16)31-15-18(9-10-20(31)25-19)29-11-13-30(14-12-29)35(3,32)33/h5-10,15H,4,11-14H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV
US Patent
| |
US Patent US10526329 (2020)
BindingDB Entry DOI: 10.7270/Q2Z60RGR |
More data for this
Ligand-Target Pair | |
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