BDBM4270 (2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-2-hydroxy-3-(naphthalen-2-ylformamido)-4-phenylbutanoyl]pyrrolidine-2-carboxamide::AHPBA 39::beta-Naphthoyl-(2S,3S)-AHPBA-4(S)-Cl-Pro-NH-t-Bu

SMILES: CC(C)(C)NC(=O)[C@@H]1C[C@H](Cl)CN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=CPIOSUOPQBAULL-CQJMVLFOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Protease (Human immunodeficiency virus type 1)	BDBM4270 ((2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-2-hydroxy...) Show SMILES CC(C)(C)NC(=O)[C@@H]1C[C@H](Cl)CN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C30H34ClN3O4/c1-30(2,3)33-28(37)25-17-23(31)18-34(25)29(38)26(35)24(15-19-9-5-4-6-10-19)32-27(36)22-14-13-20-11-7-8-12-21(20)16-22/h4-14,16,23-26,35H,15,17-18H2,1-3H3,(H,32,36)(H,33,37)/t23-,24-,25-,26-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co. Ltd.					Assay Description The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...				Bioorg Med Chem 6: 595-604 (1998) Article DOI: 10.1016/s0968-0896(98)00004-2 BindingDB Entry DOI: 10.7270/Q2QN64XQ
					More data for this Ligand-Target Pair