null
SMILES: CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)B1OC(C)(C)C(C)(C)O1
InChI Key: InChIKey=VIWHCDRFEQOOOX-IBGZPJMESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM427228 ((S)-1-((5-(7-chloroquinolin-4-yl)-3-(difluoromethy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra... | US Patent US10544120 (2020) BindingDB Entry DOI: 10.7270/Q2RF5XCX | |||||||||||
More data for this Ligand-Target Pair |