BDBM430282 US10556892, Compound 19::US10556892, Compound 8
SMILES: CCS(=O)(=O)c1ccccc1C(=O)N1CCN(C[C@@H]1C)c1nc2ccc(F)cc2s1
InChI Key: InChIKey=UKQOLPNYRVPCBM-AWEZNQCLSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human)) | BDBM430282![]() (US10556892, Compound 19 | US10556892, Compound 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PDB UniChem | PDB US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent | Assay Description HEK293 cells stably transfected with the human NAAA coding sequence cloned from a human spleen cDNA library (catalog no. 639124, Clontech, Mountain V... | US Patent US10556892 (2020) BindingDB Entry DOI: 10.7270/Q2V40XM0 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human)) | BDBM430282![]() (US10556892, Compound 19 | US10556892, Compound 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PDB UniChem | PDB US Patent | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent | Assay Description HEK293 cells stably transfected with the human NAAA coding sequence cloned from a human spleen cDNA library (catalog no. 639124, Clontech, Mountain V... | US Patent US10556892 (2020) BindingDB Entry DOI: 10.7270/Q2V40XM0 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human)) | BDBM430282![]() (US10556892, Compound 19 | US10556892, Compound 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PDB UniChem | PDB PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of human NAAA | J Med Chem 63: 7475-7490 (2020) | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human)) | BDBM430282![]() (US10556892, Compound 19 | US10556892, Compound 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PDB UniChem | PDB US Patent | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent | Assay Description HEK293 cells stably transfected with the human NAAA coding sequence cloned from a human spleen cDNA library (catalog no. 639124, Clontech, Mountain V... | US Patent US10556892 (2020) BindingDB Entry DOI: 10.7270/Q2V40XM0 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human)) | BDBM430282![]() (US10556892, Compound 19 | US10556892, Compound 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PDB UniChem | PDB PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Inhibition of NAAA (unknown origin) | Bioorg Med Chem 28: (2020) | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human)) | BDBM430282![]() (US10556892, Compound 19 | US10556892, Compound 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PDB UniChem | PDB US Patent | n/a | n/a | 554 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent | Assay Description HEK293 cells stably transfected with the human NAAA coding sequence cloned from a human spleen cDNA library (catalog no. 639124, Clontech, Mountain V... | US Patent US10556892 (2020) BindingDB Entry DOI: 10.7270/Q2V40XM0 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |