null

SMILES: COC(=O)c1ccnc(n1)N1CCN(CC1)C(C)c1ccc2CCOc2c1

InChI Key: InChIKey=PAPDPOKMWBCUOG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 430494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein O-GlcNAcase (Homo sapiens (Human))	BDBM430494 (US10556902, No 102 | US11612599, Compound 102) Show SMILES COC(=O)c1ccnc(n1)N1CCN(CC1)C(C)c1ccc2CCOc2c1 Show InChI InChI=1S/C20H24N4O3/c1-14(16-4-3-15-6-12-27-18(15)13-16)23-8-10-24(11-9-23)20-21-7-5-17(22-20)19(25)26-2/h3-5,7,13-14H,6,8-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...				Citation and Details BindingDB Entry DOI: 10.7270/Q28D015W
					More data for this Ligand-Target Pair
Protein O-GlcNAcase (Homo sapiens (Human))	BDBM430494 (US10556902, No 102 | US11612599, Compound 102) Show SMILES COC(=O)c1ccnc(n1)N1CCN(CC1)C(C)c1ccc2CCOc2c1 Show InChI InChI=1S/C20H24N4O3/c1-14(16-4-3-15-6-12-27-18(15)13-16)23-8-10-24(11-9-23)20-21-7-5-17(22-20)19(25)26-2/h3-5,7,13-14H,6,8-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Asceneuron SA US Patent					Assay Description 5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...				US Patent US10556902 (2020) BindingDB Entry DOI: 10.7270/Q2KK9F67
					More data for this Ligand-Target Pair