null

SMILES: CCN(C(c1cn(nn1)C1CC1)c1ccc(F)cc1)c1ccc2ncnc(NCC(C)(C)C)c2c1

InChI Key: InChIKey=BTTKRWWCCQEAES-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 432109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM432109 ((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CCN(C(c1cn(nn1)C1CC1)c1ccc(F)cc1)c1ccc2ncnc(NCC(C)(C)C)c2c1 Show InChI InChI=1S/C27H32FN7/c1-5-34(21-12-13-23-22(14-21)26(31-17-30-23)29-16-27(2,3)4)25(18-6-8-19(28)9-7-18)24-15-35(33-32-24)20-10-11-20/h6-9,12-15,17,20,25H,5,10-11,16H2,1-4H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.23E+3	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM432109 ((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CCN(C(c1cn(nn1)C1CC1)c1ccc(F)cc1)c1ccc2ncnc(NCC(C)(C)C)c2c1 Show InChI InChI=1S/C27H32FN7/c1-5-34(21-12-13-23-22(14-21)26(31-17-30-23)29-16-27(2,3)4)25(18-6-8-19(28)9-7-18)24-15-35(33-32-24)20-10-11-20/h6-9,12-15,17,20,25H,5,10-11,16H2,1-4H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	276	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair