null

SMILES: CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(OCCCN(CC)CCC(O)=O)cc1OC

InChI Key: InChIKey=VLBOFYFPALJWKB-NRFANRHFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 433565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM433565 ((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(OCCCN(CC)CCC(O)=O)cc1OC |r| Show InChI InChI=1S/C27H43N5O5/c1-5-8-21(12-15-33)30-26-23(19(3)29-27(28)31-26)17-20-9-10-22(18-24(20)36-4)37-16-7-13-32(6-2)14-11-25(34)35/h9-10,18,21,33H,5-8,11-17H2,1-4H3,(H,34,35)(H3,28,29,30,31)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description TLR8/NF-kB/SEAPorter™ HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the sec...				US Patent US10562861 (2020) BindingDB Entry DOI: 10.7270/Q22F7QTT
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM433565 ((S)-3-((3-(4-((2-amino-4-(1-hydroxyhexan-3-ylamino...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(OCCCN(CC)CCC(O)=O)cc1OC |r| Show InChI InChI=1S/C27H43N5O5/c1-5-8-21(12-15-33)30-26-23(19(3)29-27(28)31-26)17-20-9-10-22(18-24(20)36-4)37-16-7-13-32(6-2)14-11-25(34)35/h9-10,18,21,33H,5-8,11-17H2,1-4H3,(H,34,35)(H3,28,29,30,31)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	251	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...				US Patent US10562861 (2020) BindingDB Entry DOI: 10.7270/Q22F7QTT
					More data for this Ligand-Target Pair