BDBM43373 (5-Cyano-4-oxo-2-phenyl-3,4-dihydro-2H-[1,3]thiazin-6-ylsulfanyl)-acetic acid methyl ester::2-[(5-cyano-4-keto-2-phenyl-2,3-dihydro-1,3-thiazin-6-yl)thio]acetic acid methyl ester::2-[(5-cyano-4-oxo-2-phenyl-2,3-dihydro-1,3-thiazin-6-yl)thio]acetic acid methyl ester::MLS000556400::SMR000147717::cid_3512464::methyl 2-[(5-cyano-4-oxidanylidene-2-phenyl-2,3-dihydro-1,3-thiazin-6-yl)sulfanyl]ethanoate::methyl 2-[(5-cyano-4-oxo-2-phenyl-2,3-dihydro-1,3-thiazin-6-yl)sulfanyl]acetate

SMILES: COC(=O)CSC1=C(C#N)C(=O)NC(S1)c1ccccc1

InChI Key: InChIKey=BMVMKTNMDRHJOF-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 43373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM43373 ((5-Cyano-4-oxo-2-phenyl-3,4-dihydro-2H-[1,3]thiazi...) Show SMILES COC(=O)CSC1=C(C#N)C(=O)NC(S1)c1ccccc1 |c:6| Show InChI InChI=1S/C14H12N2O3S2/c1-19-11(17)8-20-14-10(7-15)12(18)16-13(21-14)9-5-3-2-4-6-9/h2-6,13H,8H2,1H3,(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21J984Z
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM43373 ((5-Cyano-4-oxo-2-phenyl-3,4-dihydro-2H-[1,3]thiazi...) Show SMILES COC(=O)CSC1=C(C#N)C(=O)NC(S1)c1ccccc1 |c:6| Show InChI InChI=1S/C14H12N2O3S2/c1-19-11(17)8-20-14-10(7-15)12(18)16-13(21-14)9-5-3-2-4-6-9/h2-6,13H,8H2,1H3,(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2G73C3D
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM43373 ((5-Cyano-4-oxo-2-phenyl-3,4-dihydro-2H-[1,3]thiazi...) Show SMILES COC(=O)CSC1=C(C#N)C(=O)NC(S1)c1ccccc1 |c:6| Show InChI InChI=1S/C14H12N2O3S2/c1-19-11(17)8-20-14-10(7-15)12(18)16-13(21-14)9-5-3-2-4-6-9/h2-6,13H,8H2,1H3,(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2KW5DG0
					More data for this Ligand-Target Pair