BDBM43396 (E)-N-(5-Methyl-2H-[1,2,4]triazol-3-yl)-3-phenyl-acrylamide::(E)-N-(5-methyl-1H-1,2,4-triazol-3-yl)-3-phenyl-2-propenamide::(E)-N-(5-methyl-1H-1,2,4-triazol-3-yl)-3-phenyl-acrylamide::(E)-N-(5-methyl-1H-1,2,4-triazol-3-yl)-3-phenyl-prop-2-enamide::(E)-N-(5-methyl-1H-1,2,4-triazol-3-yl)-3-phenylprop-2-enamide::MLS000591663::SMR000218688::cid_946304

SMILES: Cc1nnc(NC(=O)C=Cc2ccccc2)[nH]1

InChI Key: InChIKey=PYAVLKPKMQHZNE-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 43396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM43396 ((E)-N-(5-Methyl-2H-[1,2,4]triazol-3-yl)-3-phenyl-a...) Show SMILES Cc1nnc(NC(=O)C=Cc2ccccc2)[nH]1 |w:9.9| Show InChI InChI=1S/C12H12N4O/c1-9-13-12(16-15-9)14-11(17)8-7-10-5-3-2-4-6-10/h2-8H,1H3,(H2,13,14,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21J984Z
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM43396 ((E)-N-(5-Methyl-2H-[1,2,4]triazol-3-yl)-3-phenyl-a...) Show SMILES Cc1nnc(NC(=O)C=Cc2ccccc2)[nH]1 |w:9.9| Show InChI InChI=1S/C12H12N4O/c1-9-13-12(16-15-9)14-11(17)8-7-10-5-3-2-4-6-10/h2-8H,1H3,(H2,13,14,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.66E+3	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2G73C3D
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM43396 ((E)-N-(5-Methyl-2H-[1,2,4]triazol-3-yl)-3-phenyl-a...) Show SMILES Cc1nnc(NC(=O)C=Cc2ccccc2)[nH]1 |w:9.9| Show InChI InChI=1S/C12H12N4O/c1-9-13-12(16-15-9)14-11(17)8-7-10-5-3-2-4-6-10/h2-8H,1H3,(H2,13,14,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.52E+7	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2KW5DG0
					More data for this Ligand-Target Pair