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SMILES: Fc1cc(OCC2CCNCC2)cc2nc(CSC3CCOCC3)[nH]c(=O)c12

InChI Key: InChIKey=YYQHGXMWWCGFNC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434485   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP14 (Homo sapiens (Human))	BDBM434485 (US10562891, Example 399 | US11008308, Example 399) Show SMILES Fc1cc(OCC2CCNCC2)cc2nc(CSC3CCOCC3)[nH]c(=O)c12 Show InChI InChI=1S/C20H26FN3O3S/c21-16-9-14(27-11-13-1-5-22-6-2-13)10-17-19(16)20(25)24-18(23-17)12-28-15-3-7-26-8-4-15/h9-10,13,15,22H,1-8,11-12H2,(H,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ribon Therapeutics Inc. US Patent					Assay Description Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...				US Patent US11008308 (2021)
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP14 [1611-1801] (Homo sapiens (Human))	BDBM434485 (US10562891, Example 399 | US11008308, Example 399) Show SMILES Fc1cc(OCC2CCNCC2)cc2nc(CSC3CCOCC3)[nH]c(=O)c12 Show InChI InChI=1S/C20H26FN3O3S/c21-16-9-14(27-11-13-1-5-22-6-2-13)10-17-19(16)20(25)24-18(23-17)12-28-15-3-7-26-8-4-15/h9-10,13,15,22H,1-8,11-12H2,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ribon Therapeutics Inc. US Patent					Assay Description Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...				US Patent US10562891 (2020) BindingDB Entry DOI: 10.7270/Q290265W
					More data for this Ligand-Target Pair