BDBM43475 4-amino-2-[(E)-3-(3-bromophenyl)-1-oxoprop-2-enyl]isoindole-1,3-dione::4-amino-2-[(E)-3-(3-bromophenyl)acryloyl]isoindoline-1,3-quinone::4-amino-2-[(E)-3-(3-bromophenyl)prop-2-enoyl]isoindole-1,3-dione::4-azanyl-2-[(E)-3-(3-bromophenyl)prop-2-enoyl]isoindole-1,3-dione::MLS000516708::SMR000342877::cid_5854374

SMILES: Nc1cccc2C(=O)N(C(=O)\C=C\c3cccc(Br)c3)C(=O)c12

InChI Key: InChIKey=DGFNGIZXCZHTQK-BQYQJAHWSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 43475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM43475 (4-amino-2-[(E)-3-(3-bromophenyl)-1-oxoprop-2-enyl]...) Show SMILES Nc1cccc2C(=O)N(C(=O)\C=C\c3cccc(Br)c3)C(=O)c12 Show InChI InChI=1S/C17H11BrN2O3/c18-11-4-1-3-10(9-11)7-8-14(21)20-16(22)12-5-2-6-13(19)15(12)17(20)23/h1-9H,19H2/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	7.82E+3	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21J984Z
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM43475 (4-amino-2-[(E)-3-(3-bromophenyl)-1-oxoprop-2-enyl]...) Show SMILES Nc1cccc2C(=O)N(C(=O)\C=C\c3cccc(Br)c3)C(=O)c12 Show InChI InChI=1S/C17H11BrN2O3/c18-11-4-1-3-10(9-11)7-8-14(21)20-16(22)12-5-2-6-13(19)15(12)17(20)23/h1-9H,19H2/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2G73C3D
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM43475 (4-amino-2-[(E)-3-(3-bromophenyl)-1-oxoprop-2-enyl]...) Show SMILES Nc1cccc2C(=O)N(C(=O)\C=C\c3cccc(Br)c3)C(=O)c12 Show InChI InChI=1S/C17H11BrN2O3/c18-11-4-1-3-10(9-11)7-8-14(21)20-16(22)12-5-2-6-13(19)15(12)17(20)23/h1-9H,19H2/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2KW5DG0
					More data for this Ligand-Target Pair