BDBM43489 (E)-3-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-phenyl-prop-2-en-1-one::(E)-3-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-phenylprop-2-en-1-one::(E)-3-[(4,6-dimethyl-2-pyrimidinyl)thio]-1-phenyl-2-propen-1-one::(E)-3-[(4,6-dimethylpyrimidin-2-yl)thio]-1-phenyl-prop-2-en-1-one::3-[(4,6-dimethylpyrimidin-2-yl)thio]-1-phenylprop-2-en-1-one::MLS000851115::SMR000457358::cid_5713202

SMILES: Cc1cc(C)nc(S\C=C\C(=O)c2ccccc2)n1

InChI Key: InChIKey=MKKFBMMVSZMAGN-CMDGGOBGSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 43489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM43489 ((E)-3-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-pheny...) Show SMILES Cc1cc(C)nc(S\C=C\C(=O)c2ccccc2)n1 Show InChI InChI=1S/C15H14N2OS/c1-11-10-12(2)17-15(16-11)19-9-8-14(18)13-6-4-3-5-7-13/h3-10H,1-2H3/b9-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21J984Z
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM43489 ((E)-3-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-pheny...) Show SMILES Cc1cc(C)nc(S\C=C\C(=O)c2ccccc2)n1 Show InChI InChI=1S/C15H14N2OS/c1-11-10-12(2)17-15(16-11)19-9-8-14(18)13-6-4-3-5-7-13/h3-10H,1-2H3/b9-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	880	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2G73C3D
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM43489 ((E)-3-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-pheny...) Show SMILES Cc1cc(C)nc(S\C=C\C(=O)c2ccccc2)n1 Show InChI InChI=1S/C15H14N2OS/c1-11-10-12(2)17-15(16-11)19-9-8-14(18)13-6-4-3-5-7-13/h3-10H,1-2H3/b9-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	790	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2KW5DG0
					More data for this Ligand-Target Pair