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SMILES: F[C@@]1(CCN(C1)C#N)C(=O)Nc1cnn(c1)-c1ccccc1

InChI Key: InChIKey=IKUKFPCTXAIFDT-OAHLLOKOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436072   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
OTU domain-containing protein 7B


(Human)		BDBM436072
PNG
((R)-1-cyano-3-fluoro-N-(1-phenyl-1H-pyrazol-4-yl)p...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)Nc1cnn(c1)-c1ccccc1 |r|
Show InChI InChI=1S/C15H14FN5O/c16-15(6-7-20(10-15)11-17)14(22)19-12-8-18-21(9-12)13-4-2-1-3-5-13/h1-5,8-9H,6-7,10H2,(H,19,22)/t15-/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...

US Patent US10590075 (2020)


BindingDB Entry DOI: 10.7270/Q2280BNN
More data for this
Ligand-Target Pair