BDBM43647 (4E)-4-(1H-indol-2-ylmethylene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one::4-[(Z)-2-indolylidenemethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one::4-[(Z)-indol-2-ylidenemethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one::4-[(Z)-indol-2-ylidenemethyl]-5-methyl-2-phenyl-3-pyrazolin-3-one::MLS000724469::SMR000306063::cid_6614727
SMILES: Cc1[nH]n(-c2ccccc2)c(=O)c1C=C1C=c2ccccc2=N1
InChI Key: InChIKey=KBKCZYHTRKVJMG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal transducer and activator of transcription 3 [702-738,740-752] (Homo sapiens (Human)) | BDBM43647![]() ((4E)-4-(1H-indol-2-ylmethylene)-5-methyl-2-phenyl-...) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >229 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2S46QBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 1-alpha/beta (Homo sapiens (Human)) | BDBM43647![]() ((4E)-4-(1H-indol-2-ylmethylene)-5-methyl-2-phenyl-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PCBioAssay | n/a | n/a | n/a | n/a | >5.57E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2HM56V2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
X-box-binding protein 1 (Homo sapiens (Human)) | BDBM43647![]() ((4E)-4-(1H-indol-2-ylmethylene)-5-methyl-2-phenyl-...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay | Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NK3CGB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-inducible transcript 3 protein (Mus musculus) | BDBM43647![]() ((4E)-4-(1H-indol-2-ylmethylene)-5-methyl-2-phenyl-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay | Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q28C9TQN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-inducible transcript 3 protein (Mus musculus) | BDBM43647![]() ((4E)-4-(1H-indol-2-ylmethylene)-5-methyl-2-phenyl-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay | Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PC30VZ | |||||||||||
More data for this Ligand-Target Pair |