null

SMILES: CNCC[C@H](Oc1cccc(c1)N1CCN(C)c2ccncc2C1=O)c1cccs1

InChI Key: InChIKey=LAAINAAKDMZDHJ-NRFANRHFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 436550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436550 ((S)-1-methyl-4-(3-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1cccc(c1)N1CCN(C)c2ccncc2C1=O)c1cccs1 |r| Show InChI InChI=1S/C23H26N4O2S/c1-24-10-9-21(22-7-4-14-30-22)29-18-6-3-5-17(15-18)27-13-12-26(2)20-8-11-25-16-19(20)23(27)28/h3-8,11,14-16,21,24H,9-10,12-13H2,1-2H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020)
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436550 ((S)-1-methyl-4-(3-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1cccc(c1)N1CCN(C)c2ccncc2C1=O)c1cccs1 |r| Show InChI InChI=1S/C23H26N4O2S/c1-24-10-9-21(22-7-4-14-30-22)29-18-6-3-5-17(15-18)27-13-12-26(2)20-8-11-25-16-19(20)23(27)28/h3-8,11,14-16,21,24H,9-10,12-13H2,1-2H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020)
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM436550 ((S)-1-methyl-4-(3-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1cccc(c1)N1CCN(C)c2ccncc2C1=O)c1cccs1 |r| Show InChI InChI=1S/C23H26N4O2S/c1-24-10-9-21(22-7-4-14-30-22)29-18-6-3-5-17(15-18)27-13-12-26(2)20-8-11-25-16-19(20)23(27)28/h3-8,11,14-16,21,24H,9-10,12-13H2,1-2H3/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description NET: Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer co...				US Patent US10590140 (2020)
					More data for this Ligand-Target Pair