null
SMILES: C1Cc2n[nH]c(c2C1)-c1nnc2SCC(=Nn12)c1c[nH]c2ccccc12
InChI Key: InChIKey=BRCSLXUESJLXGP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM438755![]() (US10618914, Compound UPCDC10115 | US11111253, Comp...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM438755![]() (US10618914, Compound UPCDC10115 | US11111253, Comp...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh—Of the Commonwealth System of Higher Education US Patent | Assay Description Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, HRMS),... | US Patent US10618914 (2020) | |||||||||||
More data for this Ligand-Target Pair |